Aflibercept - EyeWiki
https://eyewiki.aao.org/Aflibercept
Overview of VEGF and Its Role in Retinal DiseaseMechanism of ActionIndications For UseIntravitreal Aflibercept Injection: dosing, Administration, and PreparationReview of Pivotal Trial Data in OphthalmologyConsiderations and ComparisonsAdditional ResourcesOphthalmology OphthalmologyIntravitreal aflibercept injection (EYLEA®; Regeneron Pharmaceuticals, Inc) was approved by the FDA in 2011 for the treatment of neovascular (wet) age-related macular degeneration (AMD) following two large clinical trials. Since then, it has also been approved for macular edema follo… OncologyZiv-aflibercept (Zaltrap®, Sanofi, developed in collaboration with Regeneron Pharmaceuticals, Inc.) in combination with 5-fluorouracil, leucovorin, irinotecan-(FOLFIRI), is indicated for patients with metastatic colorectal cancer (mCRC) that is resistant to or has progressed following an oxa…
OphthalmologyIntravitreal aflibercept injection (EYLEA®; Regeneron Pharmaceuticals, Inc) was approved by the FDA in 2011 for the treatment of neovascular (wet) age-related macular degeneration (AMD) following two large clinical trials. Since then, it has also been approved for macular edema follo…
OncologyZiv-aflibercept (Zaltrap®, Sanofi, developed in collaboration with Regeneron Pharmaceuticals, Inc.) in combination with 5-fluorouracil, leucovorin, irinotecan-(FOLFIRI), is indicated for patients with metastatic colorectal cancer (mCRC) that is resistant to or has progressed following an oxa…
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