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Inferring structural variant cancer cell fraction - Nature
https://www.nature.com/articles/s41467-020-14351-8
WEBFeb 5, 2020 · We present SVclone, a computational method for inferring the cancer cell fraction of structural variant (SV) breakpoints from whole-genome sequencing data. SVclone accurately determines the... Author: Marek Cmero, Ke Yuan, Ke Yuan, Cheng Soon Ong, Cheng Soon Ong, Jan Schröder, Pcawg Evolution, Pcawg ... Publish Year: 2020
Author: Marek Cmero, Ke Yuan, Ke Yuan, Cheng Soon Ong, Cheng Soon Ong, Jan Schröder, Pcawg Evolution, Pcawg ...
Publish Year: 2020
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DeCiFering the elusive cancer cell fraction in tumor ... - PubMed
https://pubmed.ncbi.nlm.nih.gov/34416171/
WEBOct 20, 2021 · PMCID: PMC8542635. DOI: 10.1016/j.cels.2021.07.006. Abstract. The cancer cell fraction (CCF), or proportion of cancerous cells in a tumor containing a …
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DeCiFering the elusive cancer cell fraction in tumor …
https://www.cell.com/cell-systems/pdf/S2405-4712(21)00284-2.pdf
WEBcancer cell fraction (CCF) of a somatic single-nucleotide variant, defined as the fraction of cancer cells that contain the mutation. Estimation of the CCF is complicated for …
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DeCiFering the subclonal composition of tumors: Cell …
https://www.cell.com/cell-systems/fulltext/S2405-4712(21)00376-8
WEBOct 20, 2021 · As most SNVs are retained by descendants of their common ancestor cell, we can cluster SNVs by the inferred fraction of cells carrying them, the so-called cancer cell fraction (CCF).
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DeCiFering the Elusive Cancer Cell Fraction in Tumor ... - bioRxiv
https://www.biorxiv.org/content/10.1101/2021.02.27.429196v1
WEBFeb 27, 2021 · The fundamental quantity used to measure tumor heterogeneity from somatic single-nucleotide variants (SNVs) is the Cancer Cell Fraction (CCF), or …
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A practical guide to cancer subclonal reconstruction from DNA
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7867630/
WEBCancer cell fraction (CCF): the fraction of cancer cells from the sequenced sample carrying a set of SNVs, i.e. CCF = CP / purity. It can be inferred from the VAF (f), …
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Inferring structural variant cancer cell fraction - PMC
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7002525/
WEBInferring structural variant cancer cell fraction. Marek Cmero, #1,2,3,4,5 Ke Yuan, #6,7 Cheng Soon Ong, 8,9,10 Jan Schröder, 4 PCAWG Evolution and Heterogeneity Working …
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A new method towards calculating the cancer cell fraction in cell …
https://ascopubs.org/doi/10.1200/JCO.2019.37.15_suppl.e13053
WEBMay 26, 2019 · Conclusions: We have developed a novel method to better estimate cancer cell fractions in cell-free DNA. Results showed our method is able to calculate ccf at …
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