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PCSK9 Inhibitors: A Full List, Side Effects, and More - Healthline
https://www.healthline.com/health/pcsk9-inhibitors-what-you-need-to-know
WEBSep 1, 2021 · PCSK9 inhibitors can help treat high cholesterol by directly modifying this gene to reduce the amount of LDL in your body. Learn about the PCSK9 gene, how PCSK9 inhibitors affect LDL...
DA: 61 PA: 12 MOZ Rank: 35
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PCSK9 Inhibitors: How They Manage Cholesterol and Side Effects
https://my.clevelandclinic.org/health/drugs/22550-pcsk9-inhibitors
WEBPCSK9 inhibitors are a cholesterol-lowering medicine. They work by decreasing your levels of low-density lipoprotein (LDL) cholesterol. Your provider may prescribe PCSK9 inhibitors if you have tried other medicines and still have high cholesterol.
DA: 71 PA: 11 MOZ Rank: 63
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PCSK9 inhibition: A game changer in cholesterol management
https://www.mayoclinic.org/medical-professionals/cardiovascular-diseases/news/pcsk9-inhibition-a-game-changer-in-cholesterol-management/mac-20430713
WEBPCSK9 inhibitors fill a therapeutic niche for patients with familial hypercholesterolemia or patients with statin intolerance who are not able to achieve the desired LDL-C level with conventional treatments.
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PCSK9 inhibitors: Pharmacology, adverse effects, and use
https://www.uptodate.com/contents/pcsk9-inhibitors-pharmacology-adverse-effects-and-use
WEBJan 10, 2024 · Antibodies to PCSK9 have been approved by regulatory agencies for the treatment of individuals with inadequately treated levels of LDL-cholesterol (LDL-C). They are capable of lowering LDL-C by as much as 60 percent in patients on statin therapy.
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PCSK9 Inhibitors - StatPearls - NCBI Bookshelf
https://www.ncbi.nlm.nih.gov/books/NBK448100/
WEBMay 13, 2022 · PCSK9 inhibitors are recommended for the following groups: In patients with cardiovascular disease at very high risk whose LDL-C level remains ≥70 mg/dL (≥1.8 mmol/L) on a maximally tolerated statin and ezetimibe therapy, adding a …
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PCSK 9 Inhibitors: A Short History and a New Era of Lipid …
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6686613/
WEBPCSK 9 Inhibitors: A Short History and a New Era of Lipid-lowering Therapy - PMC. Here's how you know. Journal List. Heart Views. v.20 (2); Apr-Jun 2019. PMC6686613. As a library, NLM provides access to scientific literature.
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What are PCSK9 Inhibitors and how do they work? - Drugs.com
https://www.drugs.com/medical-answers/what-pcsk9-inhibitors-how-work-3574064/
WEBMar 12, 2024 · The PCSK9 inhibitors are used for the treatment of high-risk patients with elevated cholesterol, especially when statins aren't adequate. They work by blocking PCSK9, leaving more receptors available to capture your "bad" cholesterol (LDL) for break down and removal from the blood.
DA: 13 PA: 39 MOZ Rank: 91
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PCSK9 Inhibition: From Current Advances to Evolving Future
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9562883/
WEBSep 23, 2022 · PCSK9 inhibitors are mainly used in clinical hyperlipidemia, atherosclerosis (As), and related ischemic cardiovascular diseases with significant effects and can be used as a substitute for statins and ezetimibe [ 5, 6, 7, 8 ].
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PCSK9-targeted therapies: present and future approaches
https://www.nature.com/articles/s41569-021-00634-0
WEBOct 18, 2021 · Pharmacological strategies to inhibit PCSK9 that are currently approved for clinical use or in clinical development include approaches targeting the PCSK9 protein (red boxes), such as monoclonal...
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How Do PCSK9 Inhibitors Lower Cholesterol? - WebMD
https://www.webmd.com/cholesterol-management/pcsk9-inhibitors-treatment
WEBJun 4, 2022 · PCSK9 inhibitors are a new class of drugs that lower LDL, or “bad,” cholesterol. Right now, there are two FDA-approved medications: alirocumab ( Praluent) and evolocumab ( Repatha ). Studies...
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