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Reverse transcriptase - Wikipedia
https://en.wikipedia.org/wiki/Reverse_transcriptase
WEBA reverse transcriptase (RT) is an enzyme used to generate complementary DNA (cDNA) from an RNA template, a process termed reverse transcription. Reverse transcriptases are used by viruses such as HIV and hepatitis B to replicate their genomes, by retrotransposon mobile genetic elements to proliferate within the host genome, and by eukaryotic ...
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Reverse transcriptase | Enzyme Function & Applications
https://www.britannica.com/science/reverse-transcriptase
WEBMar 13, 2024 · reverse transcriptase, an enzyme encoded from the genetic material of retroviruses that catalyzes the transcription of retrovirus RNA (ribonucleic acid) into DNA (deoxyribonucleic acid). This catalyzed transcription is the reverse process of normal cellular transcription of DNA into RNA, hence the names reverse transcriptase and …
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Reverse Transcriptase - an overview | ScienceDirect Topics
https://www.sciencedirect.com/topics/neuroscience/reverse-transcriptase
WEBReverse transcriptase is an enzyme found in retroviruses that converts the RNA genome carried in the retrovirus particle into double-stranded DNA. Reverse transcriptase first transcribes a complementary strand of DNA to make an RNA:DNA hybrid. Next, reverse transcriptase or RNase H degrades the RNA strand of the hybrid.
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Reverse Transcriptase Inhibitors - StatPearls - NCBI Bookshelf
https://www.ncbi.nlm.nih.gov/books/NBK551504/
WEBJun 25, 2023 · Reverse transcriptase inhibitors are medications used in the management and treatment of HIV. It is in the antiretroviral class of drugs. This activity reviews the indication, action, and contraindications for RTIs as a valuable agent in managing HIV (and other disorders when applicable).
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50th anniversary of the discovery of reverse transcriptase - PMC
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8120695/
WEBJan 1, 2021 · Temin’s intuitive approach to science did not end with reverse transcriptase, and in 1971, he published a speculative paper proposing that retroviruses evolved from cellular transposable elements possibly involved in normal processes, such as establishment of long-term memory (Temin, 1971).
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The Biotechnology Revolution: PCR and the Use of Reverse Transcriptase
https://www.nature.com/scitable/topicpage/the-biotechnology-revolution-pcr-and-the-use-553/
WEBJun 27, 1970 · Today, that enzyme is known as reverse transcriptase. Interestingly, in their groundbreaking papers, the two sets of scientists didn't actually identify reverse transcriptase, but they did...
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Reverse Transcriptase: From Transcriptomics to Genome Editing
https://www.cell.com/trends/biotechnology/fulltext/S0167-7799(20)30172-4
WEBReverse transcriptases (RTs) are enzymes that can generate a complementary strand of DNA (cDNA) from RNA. Coupled with PCR, RTs have been widely used to detect RNAs and to clone expressed genes. Classical retroviral RTs …
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Reverse Transcriptases: From Discovery and Applications to …
https://chemistry-europe.onlinelibrary.wiley.com/doi/10.1002/cbic.202200521
WEBNov 10, 2022 · Reverse transcriptases, enzymes that originally use RNA to write DNA, are featured in the review. They play important roles in modern research as well as diagnostics. Recent fields of activities include their tailoring, detection of RNA modifications or the reverse transcription of xeno-nucleic acids (XNAs).
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Discovery and evolution of RNA and XNA reverse transcriptase
https://www.nature.com/articles/s41557-020-0502-8
WEBJul 20, 2020 · The ability of reverse transcriptases (RTs) to synthesize a complementary DNA from natural RNA and a range of unnatural xeno nucleic acid (XNA) template chemistries, underpins key methods in...
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Reverse Transcription Basics | Thermo Fisher Scientific - US
https://www.thermofisher.com/us/en/home/life-science/cloning/cloning-learning-center/invitrogen-school-of-molecular-biology/rt-education/reverse-transcription-basics.html
WEBReverse transcription is the synthesis of DNA from an RNA template. This process is driven by RNA-dependent DNA polymerases, also known as reverse transcriptases. Reverse transcriptases occur naturally in both prokaryotic and eukaryotic organisms, as well as in retroviruses.
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