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Ziprasidone: Uses, Interactions, Mechanism of Action - DrugBank …
https://go.drugbank.com/drugs/DB00246
WEBZiprasidone is used to treat schizophrenia and bipolar disorder. 5 It can effectively reduce the rate and time of relapses in schizophrenia, and can be used to treat manic episodes in bipolar disorder although the mechanism of action is unknown. 5 Although ziprasidone is classified as an atypical antipsychotic, it appears to have a lower ...
DA: 94 PA: 71 MOZ Rank: 17
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Ziprasidone - StatPearls - NCBI Bookshelf
https://www.ncbi.nlm.nih.gov/books/NBK448157/
WEBOct 18, 2019 · Mechanism of Action. Ziprasidone is an atypical antipsychotic that has a binding affinity for dopaminergic (DA), serotonergic (5HT), adrenergic (a1), and histaminergic (HA) receptors.
DA: 76 PA: 7 MOZ Rank: 44
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Ziprasidone: Dosage, Mechanism/Onset of Action, Half-Life
https://www.medicine.com/drug/ziprasidone/hcp
WEBFeb 18, 2020 · Ziprasidone functions as an antagonist at the D 2, 5-HT 2A, and 5-HT 1D receptors and as an agonist at the 5-HT 1A receptor. Ziprasidone moderately inhibits the reuptake of serotonin and norepinephrine.
DA: 83 PA: 67 MOZ Rank: 38
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Ziprasidone - Wikipedia
https://en.wikipedia.org/wiki/Ziprasidone
WEBHow it works is not entirely clear but is believed to involve effects on serotonin and dopamine in the brain. [5] Ziprasidone was approved for medical use in the United States in 2001. [5] The pills are made up of the hydrochloride salt, ziprasidone hydrochloride.
DA: 19 PA: 88 MOZ Rank: 25
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Ziprasidone - PubMed
https://pubmed.ncbi.nlm.nih.gov/28846230/
WEBZiprasidone is an atypical antipsychotic drug used to treat schizophrenia, bipolar mania, and acute agitation in schizophrenic patients. Because it antagonizes H1 receptors, it can cause somnolence. This activity outlines the indications, mechanism of action, administration methods, significant adverse effects, contraindications, monitoring ...
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The Psychopharmacology of Ziprasidone: Receptor-Binding …
https://www.psychiatrist.com/wp-content/uploads/2021/02/16590_psychopharmacology-ziprasidone-receptor-binding-properties.pdf
WEBThe mechanism of action of atypical antipsychotics is related directly to 2 crucial neurotransmitter systems, dopamine and serotonin, that interact at various sites in the central nervous system to orchestrate a variety of physi-ologic effects.
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Ziprasidone Hydrocloride: What Role in the Management of Schizophrenia?
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3663608/
WEBFeb 15, 2011 · Compared with other first line atypical antipsychotics ziprasidone has a unique profile due to potent interaction with serotonergic receptors and lesser action upon α1 adrenergic, H1 and M1 antagonist activities.
DA: 62 PA: 47 MOZ Rank: 48
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Atypical Antipsychotic Agents - StatPearls - NCBI Bookshelf
https://www.ncbi.nlm.nih.gov/books/NBK448156/
WEBNov 7, 2022 · Mechanism of Action. Second-generation antipsychotics such as risperidone, ziprasidone, paliperidone, and aripiprazole are all potent antagonists of dopamine D2 receptors, while clozapine and quetiapine are weak D2 antagonists. These antipsychotics also have additional properties such as 5-HT2A antagonism and 5-HT1A …
DA: 9 PA: 90 MOZ Rank: 76
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Ziprasidone | Treatment & Management | Point of Care - StatPearls
https://www.statpearls.com/point-of-care/31472
WEBFeb 26, 2024 · Mechanism of Action. Ziprasidone is an atypical antipsychotic that has a binding affinity for dopaminergic (DA), serotonergic (5HT), adrenergic (α1), and histaminergic (HA) receptors.
DA: 73 PA: 14 MOZ Rank: 15
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Evidence review and clinical guidance for the use of ziprasidone …
https://annals-general-psychiatry.biomedcentral.com/articles/10.1186/1744-859X-12-1
WEBJan 24, 2013 · This action also disinhibits dopamine release in the mesocortical pathway linking the brainstem and prefrontal cortex, an action that is putatively linked to a reduction of the negative and cognitive symptoms of schizophrenia .
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